Beyond Incrementalism – Investing in the Next Blockbuster Glioblastoma Therapies (2025)
gustav2025-10-27T23:00:57+01:00Glioblastoma (GBM) remains the most aggressive and treatment-resistant primary brain tumor, with median overall survival rarely exceeding 15–20 months despite advances in surgery, imaging, and systemic therapy. The key barriers are persistent: incomplete resection, limited drug penetration across the blood–brain barrier (BBB), and a microenvironment that suppresses immune activity while promoting recurrence. In [...]